Dr. Wu is a physician-scientist with clinical expertise in neurology and epilepsy and research focus on neuromodulation and electrophysiology. Her lab investigates the neurophysiological mechanisms of how electrical stimulation influences brain functions and explores the therapeutic potential of electrical neuromodulation in treating neuropsychiatric disorders characterized by aberrant excitability and circuitry.
2022 Academic Paper Award, Cheng-Hsing Medical Foundation (Top 10% paper, publish in 2021)
2022 Young Scholar Best Paper Award, Medical College, National Cheng Kung University (2021)
2022 Young Investigator Award for Pediatric Neuropsychiatric Science
2022 Taiwan Epilepsy Society Research Paper Honorable Mention Award
2021 Innovative Research and Development Awards for Young Scholars, Honorable Mention Award, Taiwan Comprehensive University System
2021 Taiwan Epilepsy Society Research Paper Honorable Mention Award
2021 NCKU Medical College Teaching Innovativeness Honorable Mention Award
2019 Ministry of Science and Technology Research Grant (Excellent Young Investigator Grant)
2018 Academic Paper Award, Cheng-Hsing Medical Foundation
2017 The Phi Tau Phi Scholastic Honor Society Honorary Membership
2017 Ph.D. Dissertation Competition Award of Medical College, National Cheng Kung University
2017 National Cheng Kung University Hospital Research Project Competition Award (First Prize)
2016 Poster Award, Annual Conference of Taiwan Neurological Society
2016 National Cheng Kung University Hospital Research Project Competition Award (Clinical/Basic Research, 2016 First Prize, 2015 Second Prize)
2016 Ministry of Science and Technology Research Grant (Young Investigator Grant)
2015 Poster Award, Annual Conference of Taiwan Neurological Society
2015 International Conference Travel Fellowship Award, TIGP INS, Neuroscience Program in Academia Sinica (NPAS)
Associate Professor (current position), Assistant Professor, Institute of Clinical Medicine, College of Medicine, National Cheng Kung University
Clinical Assistant Professor, Neurology, College of Medicine, National Cheng Kung University
Attending Physician (current position), Resident, and Clinical Fellow, Dept. of Neurology, National Cheng Kung University Hospital
Attending Physician, Div. of Neurology, National Cheng Kung University, Dou-Liou Branch
Visiting Researcher, Institute of Cognitive Neuroscience, National Central University, Taiwan
Visiting Researcher, Institute of Neurology, UCL, Queen Square, London, UK
Visiting Associate Professor, Dept. Biomedical Engineering, Case Western Reserve University, USA
1.Yu-Chieh Hung, Yi-Jen Wu, Miao-Er Chien, Yu-Ting Lin, Cheng-Fang Tsai, Kuei-Sen Hsu*. Loss of oxytocin receptors in hilar mossy cells impairs social discrimination. Neurobiology of Disease 2023;187:106311.
2. Yi-Ting Fang†, Ye-Ting Lin†, Wu-Lung Tseng, Philip Tseng, Gia-Linh Hua, Ying-Jui Chao, *Yi-Jen Wu. Neuroimmunomodulation of vagus nerve stimulation and the therapeutic implications. Frontiers in Aging Neuroscience 2023;15:1173987.
3. Chin-Hao Chen, Tsung-Chih Tsai, Yi-Jen Wu, Kuei-Sen Hsu*. Gastric vagal afferent signaling to the basolateral amygdala mediates anxiety-like behaviors in experimental colitis mice. JCI Insight 2023;8(22):e161874.
4. Ting-Hsuan Yu, Yi-Jen Wu, Miao-Er Chien, Kuei-Sen Hsu*. Multisession anodal transcranial direct current stimulation enhances adult hippocampal neurogenesis and context discrimination in mice. Journal of Neuroscience 2023;43(4):635-646.
5. Yi-Ting Fang, Tsung-Lin Lee, Yi-Hsien Tu, Sheng-Hsiang Lin, Miao-Er Chien, Chin-Wei Huang, Kuei-Sen Hsu, Yi-Jen Wu*. Factors associated with mortality in patients with super-refractory status epilepticus. Scientific Reports 2022;12:9670.
6. Y-Jen Wu (2022). Electrophysiological and cellular mechanisms of transcranial direct current stimulation. In Ying-Zu Huang (Ed.). Noninvasive Brain Stimulation: Basic, Clinical, and Research (pp. 147-160). Taipei, Taiwan: Ho-Chi Publishing. (A book chapter written in Chinese)
7. Yi-Jen Wu*, Miao-Er Chien, Chia-Chu Chiang, Ying-Zu Huang, Dominique M Durand, Kuei-Sen Hsu*. Delta oscillation underlies the interictal spike changes after repeated transcranial direct current stimulation in a rat model of chronic seizures. Brain Stimulation 2021;14(4): 771-779.
8. Yi-Jen Wu*, Miao-Er Chien, Chih-Hsu Huang, Chia-Chu Chiang, Chou-Ching Lin, Chin-Wei Huang, Dominique M Durand, Kuei-Sen Hsu*. Transcranial direct current stimulation alleviates seizure severity in kainic acid-induced status epilepticus rats. Experimental Neurology 2020;328:113264.
9. Ting-Hsuan Yu, Yi-Jen Wu, Miao-Er Chien, Kuei-Sen Hsu*. Transcranial direct current stimulation induces hippocampal metaplasticity mediated by brain-derived neurotrophic factor. Neuropharmacology 2019;144:358-367.
10. Yi-Jen Wu, Chou-Ching Lin, Che-Ming Yeh, Miao-Er Chien, Ming-Chung Tsao, Philip Tseng, Chin-Wei Huang, Kuei-Sen Hsu*. Repeated transcranial direct current stimulation improves cognitive dysfunction and synaptic plasticity deficit in the prefrontal cortex of streptozotocin-induced diabetic rats. Brain Stimulation 2017;10(6):1079-1087.
11. Yi-Jen Wu, Philip Tseng, Han-Wei Huang, Jon-Fan Hu, Chi-Hung Juan, Kuei-Sen Hsu, Chou-Ching Lin*. The Facilitative Effect of Transcranial Direct Current Stimulation on Visuospatial Working Memory in Patients with Diabetic Polyneuropathy: A Pre– post Sham-Controlled Study. Frontiers in Human Neuroscience 2016;10:479- 489.
- Yi-Jen Wu, Philip Tseng, Chi-Fu Chang, Ming-Chyi Pai, Kuei-Sen Hsu, Chou-Ching Lin*, Chi-Hung Juan*. Modulating the interference effect on spatial working memory by applying transcranial direct current stimulation over the right dorsolateral prefrontal cortex. Brain and Cognition 2014;91:87-94.
2013-2014 National Cheng Kung University Hospital (NCKUH-10202008, PI)
2014-2015 National Cheng Kung University Hospital (NCKUH-10307016, PI)
2015-2016 National Cheng Kung University Hospital (NCKUH-10408016, PI)
2015-2016 Ministry of Science and Technology, Taiwan (MOST-104-2314-B-006-006, PI)
2016-2017 National Cheng Kung University Hospital (NCKUH-10507024, PI)
2016-2018 Ministry of Science and Technology, Taiwan (MOST-105-2628-B-006-009-MY2, PI, 傑出學者養成計畫)
2017-2018 National Cheng Kung University Hospital (NCKUH-10602005, PI)
2018-2019 National Cheng Kung University Hospital (NCKUH-10702012, PI)
2018-2019 Ministry of Science and Technology, Taiwan (MOST-107-2314-B-006-052, PI)
2019-2020 National Cheng Kung University Hospital (NCKUH-10802012, PI)
2019/3-5 Ministry of Science and Technology, Taiwan (MOST-108-2918-I-006-005, PI)
2019-2022 Ministry of Science and Technology, Taiwan (MOST-108-2628-B-006-011, PI,優秀年輕學者研究計畫)
2021-2022 National Cheng Kung University Hospital (NCKUH-11001003, Co-PI)
2022-2023 Ministry of Science and Technology, Taiwan (MOST-111-2314-B-006-100, PI)
2022-2025 National Science and Technology Council, Taiwan (NSTC 111-2218-E-007-019, Co-PI)
2023/7-2024/12 National Cheng Kung University Hospital (NCKUH-11310003, PI)
2024-2025 Ministry of Science and Technology, Taiwan (NSTC 113-2918-I-006-015, PI)
2023-2026 Ministry of Science and Technology, Taiwan (NSTC 112-2314-B-006 -061 -MY3, PI)
