Our laboratory focuses on the research of molecular mechanisms in cancer metastasis, including breast cancer (specifically triple-negative breast cancer), lung cancer, prostate cancer and various other types of cancer. The core objective is to explore the causes of high metastasis and organotropism, particularly addressing the low survival rates resulting from metastasis to the brain or nervous system. Our research scope encompasses non-coding RNA, tumor suppressor genes, and oncogenes, and we are dedicated to identifying potential diagnostic markers or therapeutic targets.
The laboratory has extensive resources, bridging basic research with clinical applications. Members of the laboratory receive multidisciplinary training to translate basic science into innovative drug development. We aim to transform these research findings into novel opportunities for clinical diagnosis and treatment.
1998.01~2001.02 Postdoctoral Research/Harvard Medical School/Harvard University
2001.02~2002.02 Assistant Professor/ Institute of Biomedical Sciences, National Sun Yat-sen University
2002.02~2003.07 Associate Professor/ Institute of Biomedical Sciences, National Sun Yat-sen University
2003.08~2007.07 Associate Researcher/Kaohsiung Veterans General Hospital
2007.08~2010.07 Associate Professor/Institute of Clinical Medicine, NCKU
2009.08~2013.07 Professor/Institute of Clinical Medicine, NCKU
2013.08~Present Distinguished Professor/Institute of Clinical Medicine, NCKU
2013.08~2017.07 Director/Laboratory Animal Center, College of Medicine, NCKU
2016.08~2017.07 Vice Dean/Office of General Affairs, College of Medicine, NCKU
2017.08~2021.04 Associate Vice President/Office of Research & Development, NCKU
2019.02~2023.01 Deputy Director/Headquarters of University Advancement, NCKU
2020.08~2021.05 Director/University Center for Bioscience and Biotechnology, NCKU
2022.02~2022.07 Director/University Center for Bioscience and Biotechnology, NCKU
2022.05~2023.01 Director/Office of Strategic Planning, NCKU
2021.02~2023.01 Secretary General/Secretariat Office, NCKU
2024.05~ Present Deputy Executive Secretary/Office of Science and Technology Policy, National Science and Technology Council, Taiwan
Therapeutic Strategies for Parenchymal and Leptomeningeal Metastasis in Triple-Negative Breast Cancer [National Science and Technology Council, 2024/8/1 ~ 2027/7/31]
Functional characterization of the non-coding RNAs mediating central nervous system (CNS) metastasis in triple-negative breast cancer [Ministry of Science and Technology, 2021/8/1 ~ 2024/7/31]
Investigation of the interplay of lncRNAs/miRNAs in TNBC metastasis [Ministry of Science and Technology, 2018/8/1 ~ 2021/7/31]
CTMP/AKT signaling promotes metastasis in triple negative breast cancer [Ministry of Science and Technology, 2017/8/1 ~ 2020/7/31]
The vesicle trafficking and anti-tumorigenic role of Rab37 small GTPase using lung cancer as a model. [Ministry of Science and Technology, 2015/8/1 ~ 2017/7/31]
Identification and functional characterization of novel long non-coding RNAs in breast cancer metastasis and tissue-specific colonization. [Ministry of Science and Technology, 2014/8/1 ~ 2015/7/31]
