faculty
CATEGORY
Infection, Immunology, Cell biology
Associate Professor
Yu-Hsiang Hsu
06-235-3535 ext.5283
NCKU Hospital Outpatient Building 7F-7062
Cytokine regulation, Osteoimmunology, New antibody drug development
PhD, Institute of Clinical Pharmacy and Pharmaceutical Sciences , National Cheng Kung University
profile
榮譽
經歷
期刊論文
研究計畫
2011-2013, Postdoctoral Fellow/Department of Biochemistry and Molecular Biology, National Cheng Kung University
2013-2022, Research Fellow/Antibody New Drug Development Center, National Cheng Kung University
2013-2015, Adjunct Assistant Professor/Department of Biochemistry and Molecular Biology, National Cheng Kung University
2015-2020, Assistant Professor/Institute of Clinical Medicine, National Cheng Kung University
2020-present, Associate Professor/Institute of Clinical Medicine, National Cheng Kung University
2022-present, Director/Antibody New Drug Development Center, National Cheng Kung University
- Huang WL, Chiu CJ, Hsu YH, Tseng YL. Radiologic and immunohistochemical correlates of cavitary pulmonary mycobacterial infection: A comparative study of tuberculosis and nontuberculous mycobacteria. J Microbiol Immunol Infect. 2026 Jan 13:S1684-1182(26)00004-6.
- Wu YR, Hsing CH, Chiu CJ, Chiang BL, Hsu YH. Eosinophil-derived interleukin-24 compromises epithelial integrity and aggravates airway remodeling in mouse models of allergic asthma. Nat Commun. 2025 Oct 20;16(1):9248.
- Tien CH, Wu YR, Cheng Y, Hsu YH. Targeting IL-20 alleviates inflammatory mechanical allodynia and reduces epidural fibrosis in post-laminectomy syndrome rat model. Int Immunopharmacol. 2025 Jan 27;146:113882.
- Chang YH, Hsing CH, Chiu CJ, Wu YR, Hsu SM, Hsu YH. Protective role of IL-17-producing γδ T cells in a laser-induced choroidal neovascularization mouse model. Journal of Neuroinflammation. 2023 Nov 25;20(1):279.
- Hsu YH, Chen CN, Chang HI, Tsai HL, Chang YH, Cheng IS, Yang YS, Huang KY. Manipulation of osteogenic and adipogenic differentiation of human degenerative disc and ligamentum flavum derived progenitor cells using IL-1β, IL-19, and IL-20. European Spine Journal. 2023 Oct;32(10):3413-3424.
- Huang LY, Chiu CJ, Hsing CH, Hsu YH. Interferon family cytokines in obesity and insulin sensitivity. Cells. 2022 Dec 14;11(24):4041.
- Chiu CJ, Liao CC, Hsu YH, Chiang BL. Circulating SSEA 1+ stem cell mediated tissue repair in allergic airway inflammation. Cellular and Molecular Life Sciences. 2022 Jun 7;79(7):347.
- Wang HH, Chen WY, Huang YH, Hsu SM, Tsao YP, Hsu YH, Chang MS. Interleukin-20 is involved in dry eye disease and is a potential therapeutic target. Journal of Biomedical Science. 2022 Jun 9;29(1):36.
- Wu YR, Hsing CH, Chiu CJ, Huang HY, Hsu YH. Roles of IL-1 and IL-10 family cytokines in the progression of systemic lupus erythematosus: friends or foes? IUBMB LIFE. 2022 Feb;74(2):143-156.
- Hsu YH, Wu CH, Chiu CJ, Chen WT, Chang YC, Wabitsch Martin, Chang MS. IL-20 is involved in obesity by modulation of adipogenesis and macrophage dysregulation. Immunology. 2021 Dec;164(4):817-833.
- Wang HH, Huang JH, Sue MH, Ho WC, Hsu YH, Chang KC, Chang MS. Interleukin-24 protects against liver injury in mouse models. EBioMedicine. 2021 Feb: 64:103213.
- SW Lu, HC Pan, YH Hsu, KC Chang, LW Wu, WY Chen, MS Chang. IL-20 antagonist suppresses PD-L1 expression and prolongs survival in pancreatic cancer models. Nature communications. 2020 Sep 14;11(1):4611.
- Chen LH, Yeh YM, Chen YF, Hsu YH, Wang HH, Lin PC, Chang LY, Lin CK, Chang MS, Shen MR. Targeting interleukin-20 alleviates paclitaxel-induced peripheral neuropathy. Pain. 2020 Jun;161(6):1237-1254.
- Hsu YH, Lee JS, Chiu YS, Jou IM, Chang MS. Anti-IL-20 antibody improved motor function and reduced glial scar formation after traumatic spinal cord injury in rats. Journal of Neuroinflammation. 2020 May 14;17(1):156.
- Lin TY, Chiu CJ, Kuan CH, Chen FH, Shen YC, Wu CH, Hsu YH. IL-29 promoted obesity-induced inflammation and insulin resistance. Cellular & Molecular Immunology. 2020 Apr;17(4):369-379.
- Lin TY and Hsu YH. IL-20 in acute kidney injury: Role in pathogenesis and potential as a therapeutic target. International Journal of Molecular Sciences. 2020 Feb 3;21(3):1009.
- Hsu YH, Lin RM, Chiu YS, Liu WL, Huang KY. Effects of IL-1β, IL-20, and BMP-2 on intervertebral disc inflammation under hypoxia. Journal of Clinical Medicine. 2020 Jan 4;9(1):140.
- Lin TC, Liu WC, Hsu YH, Lin JJ, Chiu YC, Chiu HC, Cheng PN, Chen CY, Chang TT, and Wu IC. Insulin resistance associated disorders pivoting long-term hepatitis B surface antigen decline during entecavir therapy. Journal of Clinical Medicine. 2019 Nov 6;8(11):1892.
